FANCD2 re-expression is associated with glioma grade and chemical inhibition of the Fanconi Anaemia pathway sensitises gliomas to chemotherapeutic agents

Brain tumours kill more children and adults under 40 than any other cancer. Around half of primary brain tumours are glioblastoma multiforme (GBMs) where treatment remains a significant challenge. GBM survival rates have improved little over the last 40 years, thus highlighting an unmet need for the...

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Main Authors: Patil, Abhijit A., Sayal, Parag, Depondt, Marie-Lise, Beveridge, Ryan D., Roylance, Anthony, Kriplani, Deepti H., Myers, Katie N., Cox, Angela, Jellinek, David, Fernando, Malee, Carroll, Thomas A., Collis, Spencer J.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2014
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4171640/
https://ncbi.nlm.nih.gov/pubmed/25071006
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