Cdc6 cooperates with c-Myc to promote genome instability and epithelial to mesenchymal transition (EMT) in zebrafish

Aberration in DNA replication is a major cause to genome instability that is a hallmark of cancer cells. Cell division cycle 6 (Cdc6) and c-Myc have a critical role in the initiation of DNA replication. However, whether their interaction induces epithelial-mesenchymal transition (EMT) and promotes t...

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Autors principals: Chen, Ching-Hung, Lin, Dar-Shong, Cheng, Chieh-Wen, Lin, Chun-Ju, Lo, Yu-Kang, Yen, Chueh-Chuan, Lee, Alan Yueh-Luen, Hsiao, Chung-Der
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2014
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4171631/
https://ncbi.nlm.nih.gov/pubmed/25051368
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