Suppression of the breakthrough of human immunodeficiency virus type 1 (HIV-1) in cell culture by thiocarboxanilide derivatives when used individually or in combination with other HIV-1-specific inhibitors (i.e., TSAO derivatives).

Five structurally related thiophene and furane analogues of the oxathiin carboxanilide derivative NSC 615985 (UC84) (designated UC10, UC68, UC81, UC42, and UC16) were identified as potent inhibitors of HIV-1 replication in cell culture and HIV-1 reverse transcriptase activity. These compounds were m...

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Bibliografische gegevens

Gepubliceerd in:	Proc Natl Acad Sci U S A
Hoofdauteurs:	Balzarini, J, Pérez-Pérez, M J, Vélazquez, S, San-Félix, A, Camarasa, M J, De Clercq, E, Karlsson, A
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	National Academy of Sciences 1995
Onderwerpen:	Research Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41716/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7539917/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.12.5470
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