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Induction of integrin α(2) in a highly bone metastatic human prostate cancer cell line: roles of RANKL and AR under three-dimensional suspension culture

BACKGROUND: Prostate cancer (PCa) bone metastasis can be markedly enhanced by increased receptor activator of NF kappa-B ligand (RANKL) expression in PCa cells. Molecular mechanisms that account for the increased predilection of PCa for bone include increased bone turnover, promotion of PCa cell gro...

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Detalhes bibliográficos
Main Authors: Ziaee, Shabnam, Chung, Leland WK
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4171564/
https://ncbi.nlm.nih.gov/pubmed/25200184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-208
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