Novel Camelid Antibody Fragments Targeting Recombinant Nucleoprotein of Araucaria hantavirus: A Prototype for an Early Diagnosis of Hantavirus Pulmonary Syndrome

In addition to conventional antibodies, camelids produce immunoglobulins G composed exclusively of heavy chains in which the antigen binding site is formed only by single domains called VHH. Their particular characteristics make VHHs interesting tools for drug-delivery, passive immunotherapy and hig...

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Hauptverfasser: Pereira, Soraya S., Moreira-Dill, Leandro S., Morais, Michelle S. S., Prado, Nidiane D. R., Barros, Marcos L., Koishi, Andrea C., Mazarrotto, Giovanny A. C. A., Gonçalves, Giselle M., Zuliani, Juliana P., Calderon, Leonardo A., Soares, Andreimar M., Pereira da Silva, Luiz H., Duarte dos Santos, Claudia N., Fernandes, Carla F. C., Stabeli, Rodrigo G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4171512/
https://ncbi.nlm.nih.gov/pubmed/25243411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108067
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