Leukemic Stem Cell Frequency: A Strong Biomarker for Clinical Outcome in Acute Myeloid Leukemia

INTRODUCTION: Treatment failure in acute myeloid leukemia is probably caused by the presence of leukemia initiating cells, also referred to as leukemic stem cells, at diagnosis and their persistence after therapy. Specific identification of leukemia stem cells and their discrimination from normal he...

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Main Authors: Terwijn, Monique, Zeijlemaker, Wendelien, Kelder, Angèle, Rutten, Arjo P., Snel, Alexander N., Scholten, Willemijn J., Pabst, Thomas, Verhoef, Gregor, Löwenberg, Bob, Zweegman, Sonja, Ossenkoppele, Gert J., Schuurhuis, Gerrit J.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4171508/
https://ncbi.nlm.nih.gov/pubmed/25244440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107587
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