APOE-epsilon4 and aging of medial temporal lobe gray matter in healthy adults older than 50 years

Atrophy of the hippocampus and surrounding temporal regions occurs in Alzheimer’s disease (AD). APOE ε4, the major genetic risk factor for late-onset AD, has been associated with smaller volume in these regions before amyloidosis can be detected by AD biomarkers. To examine APOE ε4 effects in relati...

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Detalhes bibliográficos
Main Authors: Taylor, Joy L., Scanlon, Blake K., Farrell, Michelle, Hernandez, Beatriz, Adamson, Maheen M., Ashford, J. Wesson, Noda, Art, Murphy, Greer M., Weiner, Michael W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4171437/
https://ncbi.nlm.nih.gov/pubmed/24929969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2014.05.011
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