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Distinct Signalling Pathways of Murine Histamine H(1)- and H(4)-Receptors Expressed at Comparable Levels in HEK293 Cells

Histamine (HA) is recognized by its target cells via four G-protein-coupled receptors, referred to as histamine H(1)-receptor (H(1)R), H(2)R, H(3)R, and H(4)R. Both H(1)R and H(4)R exert pro-inflammatory functions. However, their signal transduction pathways have never been analyzed in a directly co...

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Autors principals: Beermann, Silke, Vauth, Marcus, Hein, Rabea, Seifert, Roland, Neumann, Detlef
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4171377/
https://ncbi.nlm.nih.gov/pubmed/25243776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107481
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