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Change or Die: Targeting Adaptive Signaling to Kinase Inhibition in Cancer Cells

Small molecule kinase inhibitors have proven enormously successful at delivering impressive responses in patients with cancers as diverse as chronic myeloid-leukemia, melanoma, breast cancer and small cell lung cancer. Despite this, resistance is commonplace and most patients ultimately fail therapy...

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Autors principals: Rebecca, Vito W., Smalley, Keiran S. M.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4171341/
https://ncbi.nlm.nih.gov/pubmed/25107706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2014.07.031
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