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Silencing SMYD3 in hepatoma demethylates RIZI promoter induces apoptosis and inhibits cell proliferation and migration

AIM: To investigate the role of SMYD3 in hepatocellular carcinoma (HCC) development and progression and to verify whether its regulation activity was through RIZ1 inactivation. METHODS: Expression of SMYD3 in HCC cell lines and tissues were measured; silencing of SMYD3 by RNA interference (RNAi) was...

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Main Authors: Chen, Li-Bo, Xu, Jun-Yao, Yang, Zhen, Wang, Guo-Bin
Formato: Artigo
Idioma:Inglês
Publicado: Baishideng Publishing Group Inc 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4171257/
https://ncbi.nlm.nih.gov/pubmed/17963297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v13.i43.5718
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