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Phase II trial of bortezomib plus doxorubicin in hepatocellular carcinoma (E6202): a trial of the Eastern Cooperative Oncology Group

PURPOSE: To evaluate the efficacy and tolerability of bortezomib in combination with doxorubicin in patients with advanced hepatocellular carcinoma, and to correlate pharmaco-dynamic markers of proteasome inhibition with response and survival. Experimental Design This phase II, open-label, multi-cen...

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Main Authors: Ciombor, Kristen K., Feng, Yang, Benson, Al Bowen, Su, Yingjun, Horton, Linda, Short, Sarah P., Kauh, John Sae Wook, Staley, Charles, Mulcahy, Mary, Powell, Mark, Amiri, Katayoun I., Richmond, Ann, Berlin, Jordan
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4171216/
https://ncbi.nlm.nih.gov/pubmed/24890858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-014-0111-8
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