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Destruction of the hepatocyte junction by intercellular invasion of Leptospira causes jaundice in a hamster model of Weil's disease

Weil's disease, the most severe form of leptospirosis, is characterized by jaundice, haemorrhage and renal failure. The mechanisms of jaundice caused by pathogenic Leptospira remain unclear. We therefore aimed to elucidate the mechanisms by integrating histopathological changes with serum bioch...

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Detalhes bibliográficos
Main Authors: Miyahara, Satoshi, Saito, Mitsumasa, Kanemaru, Takaaki, Villanueva, Sharon Y A M, Gloriani, Nina G, Yoshida, Shin-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4170969/
https://ncbi.nlm.nih.gov/pubmed/24945433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/iep.12085
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