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Modeling, Molecular Dynamics Simulation, and Mutation Validation for Structure of Cannabinoid Receptor 2 Based on Known Crystal Structures of GPCRs

[Image: see text] The cannabinoid receptor 2 (CB2) plays an important role in the immune system. Although a few of GPCRs crystallographic structures have been reported, it is still challenging to obtain functional transmembrane proteins and high resolution X-ray crystal structures, such as for the C...

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Detalhes bibliográficos
Main Authors: Feng, Zhiwei, Alqarni, Mohammed Hamed, Yang, Peng, Tong, Qin, Chowdhury, Ananda, Wang, Lirong, Xie, Xiang-Qun
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4170816/
https://ncbi.nlm.nih.gov/pubmed/25141027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ci5002718
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