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Silencing of Plasma Membrane Ca(2+)-ATPase Isoforms 2 and 3 Impairs Energy Metabolism in Differentiating PC12 Cells

A close link between Ca(2+), ATP level, and neurogenesis is apparent; however, the molecular mechanisms of this relationship have not been completely elucidated. Transient elevations of cytosolic Ca(2+) may boost ATP synthesis, but ATP is also consumed by ion pumps to maintain a low Ca(2+) in cytoso...

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Autors principals: Boczek, Tomasz, Lisek, Malwina, Ferenc, Bozena, Kowalski, Antoni, Wiktorska, Magdalena, Zylinska, Ludmila
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4170788/
https://ncbi.nlm.nih.gov/pubmed/25276815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/735106
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