Hedgehog signaling sensitizes Glioma stem cells to endogenous nano-irradiation

The existence of therapy resistant glioma stem cells is responsible for the high recurrence rate and incurability of glioblastomas. The Hedgehog pathway activity plays an essential role for self-renewal capacity and survival of glioma stem cells. We examined the potential of the Sonic hedgehog ligan...

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Autors principals: Morgenroth, Agnieszka, Vogg, Andreas T. J., Ermert, Katja, Zlatopolskiy, Boris, Mottaghy, Felix M.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2014
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4170618/
https://ncbi.nlm.nih.gov/pubmed/24978848
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