Thrombospondin 1 promotes an aggressive phenotype through epithelial-to-mesenchymal transition in human melanoma

Epithelial-to-mesenchymal transition (EMT), in which epithelial cells loose their polarity and become motile mesenchymal cells, is a determinant of melanoma metastasis. We compared gene expression signatures of mesenchymal-like melanoma cells with those of epithelial-like melanoma cells, and identif...

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Auteurs principaux: Jayachandran, Aparna, Anaka, Matthew, Prithviraj, Prashanth, Hudson, Christopher, McKeown, Sonja J, Lo, Pu-Han, Vella, Laura J, Goding, Colin R, Cebon, Jonathan, Behren, Andreas
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2014
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4170613/
https://ncbi.nlm.nih.gov/pubmed/25051363
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