Identification of functionally important helical faces in transmembrane segments by scanning mutagenesis.
We applied mutational analysis to a protein domain that functions in neither catalysis nor binding but, rather, in transmembrane signaling. The domain is part of chemoreceptor Trg from Escherichia coli. It contains four transmembrane segments, two from each subunit of the homodimer. We used cysteine...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1995
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41705/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7777522/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.12.5416 |
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