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Interferon gamma signals via a high-affinity multisubunit receptor complex that contains two types of polypeptide chain.

Signaling by interferon gamma (IFN-gamma) requires two structurally related cell surface proteins: a ligand-binding polypeptide, known as the IFN-gamma receptor (IFN-gamma R), and an accessory factor. However, it is not known whether IFN-gamma forms a ternary complex with the IFN-gamma R and accesso...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Marsters, S A, Pennica, D, Bach, E, Schreiber, R D, Ashkenazi, A
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1995
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41702/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7777519/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.12.5401
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