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Microarray Analysis of Gene Expression Reveals that Cyclo-oxygenase-2 Gene Therapy Up-regulates Hematopoiesis and Down-regulates Inflammation During Endochondral Bone Fracture Healing

BACKGROUND: Cyclo-oxygenase-2 (Cox-2) is an inflammatory mediator that is necessary for the tissue repair, including bone fracture healing. Although the application of Cox-2 gene therapy to a murine closed femoral fracture has accelerated bony union, but the beneficial effect was not observed until...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lau, K.-H. William, Popa, Nicoleta L., Rundle, Charles H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Korean Society for Bone and Mineral Research 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4170080/
https://ncbi.nlm.nih.gov/pubmed/25247155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.11005/jbm.2014.21.3.169
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