Brief postnatal exposure to phenobarbital impairs passive-avoidance learning and sensorimotor gating in rats

Phenobarbital is the most commonly utilized drug for the treatment of neonatal seizures. However, mounting preclinical evidence suggests that even brief exposure to phenobarbital in the neonatal period can induce neuronal apoptosis, alterations in synaptic development, and long-lasting changes in be...

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Bibliographic Details
Main Authors: Gutherz, Samuel B., Kulick, Catherine V., Soper, Colin, Kondratyev, Alexei, Gale, Karen, Forcelli, Patrick A.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4170015/
https://ncbi.nlm.nih.gov/pubmed/25112558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yebeh.2014.07.010
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