Blockade of IL-6 Trans Signaling Attenuates Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF) is a lethal lung disease with progressive fibrosis and death within 2–3 y of diagnosis. IPF incidence and prevalence rates are increasing annually with few effective treatments available. Inhibition of IL-6 results in the attenuation of pulmonary fibrosis in mice....

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Autori principali: Le, Thanh-Thuy T., Karmouty-Quintana, Harry, Melicoff, Ernestina, Le, Thanh-Truc T., Weng, Tingting, Chen, Ning-Yuan, Pedroza, Mesias, Zhou, Yang, Davies, Jonathan, Philip, Kemly, Molina, Jose, Luo, Fayong, George, Anuh T., Garcia-Morales, Luis J., Bunge, Raquel R., Bruckner, Brian A., Loebe, Matthias, Seethamraju, Harish, Agarwal, Sandeep K., Blackburn, Michael R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: AAI 2014
Soggetti:
Molecular and Structural Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169999/
https://ncbi.nlm.nih.gov/pubmed/25172494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302470
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