Physicochemical signatures of nanoparticle-dependent complement activation

Nanoparticles are potentially powerful therapeutic tools that have the capacity to target drug payloads and imaging agents. However, some nanoparticles can activate complement, a branch of the innate immune system, and cause adverse side-effects. Recently, we employed an in vitro hemolysis assay to...

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Main Authors: Thomas, Dennis G., Chikkagoudar, Satish, Heredia-Langer, Alejandro, Tardiff, Mark F., Xu, Zhixiang, Hourcade, Dennis E., Pham, Christine T. N., Lanza, Gregory M., Weinberger, Kilian Q., Baker, Nathan A.
Format: Artigo
Jezik:Inglês
Izdano: 2014
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169987/
https://ncbi.nlm.nih.gov/pubmed/25254068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1749-4699/7/1/015003
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