Multi-Center Biologic Assignment Trial Comparing Reduced Intensity Allogeneic Hematopoietic Cell Transplant to Hypomethylating Therapy or Best Supportive Care in Patients Aged 50-75 with Intermediate-2 and High Risk Myelodysplastic Syndrome Blood and Marrow Transplant Clinical Trials Network #1102 Study Rationale, Design and Methods

The introduction of reduced intensity conditioning regimens (RIC) made it possible to offer allogeneic hematopoietic cell transplantation (alloHCT) to older patients with myelodysplastic syndromes (MDS). However, the relative risks and benefits of alloHCT compared to novel non-transplant therapies c...

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Main Authors: Saber, Wael, Le Rademacher, Jennifer, Sekeres, Mikkael, Logan, Brent, Lewis, Moira, Mendizabal, Adam, Leifer, Eric, Appelbaum, Frederick R., Horowitz, Mary M, Nakamura, Ryotaro, Cutler, Corey S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169902/
https://ncbi.nlm.nih.gov/pubmed/24972249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2014.06.010
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