Design and Anticipated Outcomes of the eMERGE-PGx Project: A Multi-Center Pilot for Pre-Emptive Pharmacogenomics in Electronic Health Record Systems

We describe here the design and initial implementation of the eMERGE-PGx project. eMERGE-PGx, a partnership of the eMERGE and PGRN consortia, has three objectives : 1) Deploy PGRNseq, a next-generation sequencing platform assessing sequence variation in 84 proposed pharmacogenes, in nearly 9,000 pat...

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Detalhes bibliográficos
Main Authors: Rasmussen-Torvik, Laura J., Stallings, Sarah C., Gordon, Adam S., Almoguera, Berta, Basford, Melissa A., Bielinski, Suzette J., Brautbar, Ariel, Brilliant, Murray, Carrell, David S., Connolly, John, Crosslin, David R., Doheny, Kimberly F., Gallego, Carlos J., Gottesman, Omri, Kim, Daniel Seung, Leppig, Kathleen A., Li, Rongling, Lin, Simon, Manzi, Shannon, Mejia, Ana R., Pacheco, Jennifer A., Pan, Vivian, Pathak, Jyotishman, Perry, Cassandra L., Peterson, Josh F., Prows, Cynthia A., Ralston, James, Rasmussen, Luke V., Ritchie, Marylyn D., Sadhasivam, Senthilkumar, Scott, Stuart A., Smith, Maureen, Vega, Aida, Vinks, Alexander A., Volpi, Simona, Wolf, Wendy A., Bottinger, Erwin, Chisholm, Rex L., Chute, Christopher G., Haines, Jonathan L., Harley, John B., Keating, Brendan, Holm, Ingrid A., Kullo, Iftikhar J., Jarvik, Gail P., Larson, Eric B., Manolio, Teri, McCarty, Catherine A., Nickerson, Deborah A., Scherer, Steven E., Williams, Marc S., Roden, Dan M., Denny, Joshua C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169732/
https://ncbi.nlm.nih.gov/pubmed/24960519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2014.137
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