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Bcl-xL regulates CD1d-mediated antigen presentation to NKT cells by altering CD1d trafficking through the endocytic pathway

Natural killer T (NKT) cells are a unique subset of T cells that recognize glycolipid antigens presented in the context of CD1d molecules. NKT cells mount strong anti-tumor responses and are a major focus in developing effective cancer immunotherapy. It is known that CD1d molecules are constantly in...

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Detalhes bibliográficos
Main Authors: Subrahmanyam, Priyanka B., Carey, Gregory B., Webb, Tonya J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169674/
https://ncbi.nlm.nih.gov/pubmed/25070854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400155
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