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The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling

Despite an enormous interest in the role of extracellular vesicles, including exosomes, in cancer and their use as biomarkers for diagnosis, prognosis, drug response and recurrence, there is no consensus on dependable isolation protocols. We provide a comparative evaluation of 4 exosome isolation pr...

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Detalhes bibliográficos
Main Authors: Van Deun, Jan, Mestdagh, Pieter, Sormunen, Raija, Cocquyt, Veronique, Vermaelen, Karim, Vandesompele, Jo, Bracke, Marc, De Wever, Olivier, Hendrix, An
Formato: Artigo
Idioma:Inglês
Publicado em: Co-Action Publishing 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169610/
https://ncbi.nlm.nih.gov/pubmed/25317274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3402/jev.v3.24858
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