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PIWI Proteins Are Dispensable for Mouse Somatic Development and Reprogramming of Fibroblasts into Pluripotent Stem Cells

PIWI proteins play essential and conserved roles in germline development, including germline stem cell maintenance and meiosis. Because germline regulators such as OCT4, NANOG, and SOX2 are known to be potent factors that reprogram differentiated somatic cells into induced pluripotent stem cells (iP...

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Detalhes bibliográficos
Main Authors: Cheng, Ee-Chun, Kang, Dongwan, Wang, Zhong, Lin, Haifan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169525/
https://ncbi.nlm.nih.gov/pubmed/25238487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097821
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