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Exploitation of Mycobacterium tuberculosis Reporter Strains to Probe the Impact of Vaccination at Sites of Infection

Mycobacterium tuberculosis (Mtb) remains a major public health problem, with an effective vaccine continuing to prove elusive. Progress in vaccination strategies has been hampered by a lack of appreciation of the bacterium's response to dynamic changes in the host immune environment. Here, we u...

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Detalhes bibliográficos
Main Authors: Sukumar, Neelima, Tan, Shumin, Aldridge, Bree B., Russell, David G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169503/
https://ncbi.nlm.nih.gov/pubmed/25233380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004394
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