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Epiplakin Deficiency Aggravates Murine Caerulein-Induced Acute Pancreatitis and Favors the Formation of Acinar Keratin Granules

Epiplakin, a member of the plakin protein family, is exclusively expressed in epithelial tissues and was shown to bind to keratins. Epiplakin-deficient (EPPK(−/−)) mice showed no obvious spontaneous phenotype, however, EPPK(−/−) keratinocytes displayed faster keratin network breakdown in response to...

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Detalhes bibliográficos
Main Authors: Wögenstein, Karl L., Szabo, Sandra, Lunova, Mariia, Wiche, Gerhard, Haybaeck, Johannes, Strnad, Pavel, Boor, Peter, Wagner, Martin, Fuchs, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169488/
https://ncbi.nlm.nih.gov/pubmed/25232867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108323
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