Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 Deficiency Reduces Insulin Sensitivity in High-Fat Diet-Fed Mice

Adipose tissue inflammation is considered an important contributor to insulin resistance. Mitogen-activated protein kinase-activated protein kinase 2 (MK2) is a major downstream target of p38 MAPK and enhances inflammatory processes. In line with the role of MK2 as contributor to inflammation, MK2(−...

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Main Authors: de Boer, Jan Freark, Dikkers, Arne, Jurdzinski, Angelika, von Felden, Johann, Gaestel, Matthias, Bavendiek, Udo, Tietge, Uwe J. F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169416/
https://ncbi.nlm.nih.gov/pubmed/25233471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106300
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