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Endostar, a Modified Recombinant Human Endostatin, Suppresses Angiogenesis through Inhibition of Wnt/β-Catenin Signaling Pathway

Endostar, a novel modified recombinant human endostatin, is now widely studied for the treatment of diseases that are characterized or caused by pathological angiogenesis. However, its molecular mechanism remains unclear. In this study, we investigated the effects of Endostar on the Wnt/β-catenin si...

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Detalhes bibliográficos
Main Authors: Xu, Xiaoming, Mao, Wei, Chen, Qian, Zhuang, Qin, Wang, Lihui, Dai, Jin, Wang, Haibing, Huang, Zhaoquan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169397/
https://ncbi.nlm.nih.gov/pubmed/25232946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107463
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