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Detection of anti-Ro, La, Smith and RNP autoantibodies by autoantigen microarray analysis and interferon-alpha induction in juvenile dermatomyositis

OBJECTIVE: To evaluate serum interferon-α (IFNα) activity in the context of autoantibody profiles in patients with juvenile dermatomyositis (JDM). METHODS: Sera from 36 JDM patients were analyzed. Autoantibody profiles were determined by probing microarrays, fabricated with ~80 distinct autoantigens...

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Bibliographische Detailangaben
Hauptverfasser: Balboni, Imelda, Niewold, Timothy B., Morgan, Gabrielle, Limb, Cindy, Eloranta, Maija-Leena, Rönnblom, Lars, Utz, Paul J., Pachman, Lauren M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169271/
https://ncbi.nlm.nih.gov/pubmed/23740815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38038
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