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Is Higher Lactate an Indicator of Tumor Metastatic Risk? A Pilot MRS Study Using Hyperpolarized (13)C-Pyruvate

RATIONALE AND OBJECTIVES: Cancer cells generate more lactate than normal cells under aerobic and hypoxic conditions – exhibiting the so-called Warburg effect. However, the relationship between the Warburg effect and tumor metastatic potential remains controversial. We intend to investigate whether t...

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Autori principali: Xu, He N., Kadlececk, Stephen, Profka, Harrilla, Glickson, Jerry D., Rizi, Rahim, Li, Lin Z.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169113/
https://ncbi.nlm.nih.gov/pubmed/24439336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.acra.2013.11.014
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