Rapid and multi-level characterization of trastuzumab using sheathless capillary electrophoresis-tandem mass spectrometry

Monoclonal antibodies (mAbs) are highly complex proteins that display a wide range of microheterogeneity that requires multiple analytical methods for full structure assessment and quality control. As a consequence, the characterization of mAbs on different levels is particularly product - and time...

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Autori principali: Gahoual, Rabah, Burr, Alicia, Busnel, Jean-Marc, Kuhn, Lauriane, Hammann, Phillipe, Beck, Alain, François, Yannis-Nicolas, Leize-Wagner, Emmanuelle
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169039/
https://ncbi.nlm.nih.gov/pubmed/23563524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.23995
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