Genome-wide DNA methylation profiling in rheumatoid arthritis identifies disease-associated methylation changes that are distinct to individual T- and B-lymphocyte populations

Changes to the DNA methylome have been described in patients with rheumatoid arthritis (RA). In previous work, we reported genome-wide methylation differences in T-lymphocyte and B-lymphocyte populations from healthy individuals. Now, using HumanMethylation450 BeadChips to interrogate genome-wide DN...

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Detalhes bibliográficos
Main Authors: Glossop, John R, Emes, Richard D, Nixon, Nicola B, Haworth, Kim E, Packham, Jon C, Dawes, Peter T, Fryer, Anthony A, Mattey, Derek L, Farrell, William E
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169015/
https://ncbi.nlm.nih.gov/pubmed/25147922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.29718
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