Promoter hypermethylation using 24-gene array in early head and neck cancer: Better outcome in oral than in oropharyngeal cancer

Silencing of tumor suppressor genes (TSGs) by DNA promoter hypermethylation is an early event in carcinogenesis and a potential target for personalized cancer treatment. In head and neck cancer, little is known about the role of promoter hypermethylation in survival. Using methylation specific multi...

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Bibliographische Detailangaben
Hauptverfasser: Noorlag, Rob, van Kempen, Pauline MW, Moelans, Cathy B, de Jong, Rick, Blok, Laura ER, Koole, Ronald, Grolman, Wilko, van Diest, Paul J, van Es, Robert JJ, Willems, Stefan M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2014
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169014/
https://ncbi.nlm.nih.gov/pubmed/25147921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.29785
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