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Quantitative Analysis of T Cell Receptor Complex Interaction Sites Using Genetically Encoded Photo-Cross-Linkers

[Image: see text] The T cell receptor (TCR)-cluster of differentiation 3 (CD3) signaling complex plays an important role in initiation of adaptive immune responses, but weak interactions have obstructed delineation of the individual TCR-CD3 subunit interactions during T cell signaling. Here, we demo...

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Detalhes bibliográficos
Main Authors: Wang, Wenjuan, Li, Tianqi, Felsovalyi, Klara, Chen, Chunlai, Cardozo, Timothy, Krogsgaard, Michelle
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4168801/
https://ncbi.nlm.nih.gov/pubmed/25061810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb500351s
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