Alterations in Energy/Redox Metabolism Induced by Mitochondrial and Environmental Toxins: A Specific Role for Glucose-6-Phosphate-Dehydrogenase and the Pentose Phosphate Pathway in Paraquat Toxicity

[Image: see text] Parkinson’s disease (PD) is a multifactorial disorder with a complex etiology including genetic risk factors, environmental exposures, and aging. While energy failure and oxidative stress have largely been associated with the loss of dopaminergic cells in PD and the toxicity induce...

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Main Authors: Lei, Shulei, Zavala-Flores, Laura, Garcia-Garcia, Aracely, Nandakumar, Renu, Huang, Yuting, Madayiputhiya, Nandakumar, Stanton, Robert C., Dodds, Eric D., Powers, Robert, Franco, Rodrigo
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2014
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4168797/
https://ncbi.nlm.nih.gov/pubmed/24937102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb400894a
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