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Nitroreductase-Activatable Morpholino Oligonucleotides for in Vivo Gene Silencing

[Image: see text] Phosphorodiamidate morpholino oligonucleotides are widely used to interrogate gene function in whole organisms, and light-activatable derivatives can reveal spatial and temporal differences in gene activity. We describe here a new class of caged morpholino oligonucleotides that can...

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Bibliografische gegevens
Hoofdauteurs: Yamazoe, Sayumi, McQuade, Lindsey E., Chen, James K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Chemical Society 2014
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4168795/
https://ncbi.nlm.nih.gov/pubmed/25069083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb500429u
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