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Biology of adeno-associated viral vectors in the central nervous system

Gene therapy is a promising approach for treating a spectrum of neurological and neurodegenerative disorders by delivering corrective genes to the central nervous system (CNS). In particular, adeno-associated viruses (AAVs) have emerged as promising tools for clinical gene transfer in a broad range...

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Detalhes bibliográficos
Main Authors: Murlidharan, Giridhar, Samulski, Richard J., Asokan, Aravind
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4168676/
https://ncbi.nlm.nih.gov/pubmed/25285067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2014.00076
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