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Model-based clinical pharmacology profiling of ipilimumab in patients with advanced melanoma
AIM: Ipilimumab is a fully human, monoclonal antibody that blocks cytotoxic T-lymphocyte antigen-4. The objective of the present study was to characterize the clinical pharmacology profile of ipilimumab using a population pharmacokinetic (PPK) approach. METHODS: The PPK model was developed using 209...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4168385/ https://ncbi.nlm.nih.gov/pubmed/24433434 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12323 |
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