Pharmacokinetic and Pharmacodynamic Profiles of Canagliflozin in Japanese Patients with Type 2 Diabetes Mellitus and Moderate Renal Impairment

BACKGROUND AND OBJECTIVES: This study examined the effects of moderate renal impairment on the pharmacokinetics and pharmacodynamics of canagliflozin in Japanese patients with type 2 diabetes mellitus. METHODS: Japanese patients with stable type 2 diabetes (12 with moderate renal impairment and 12 w...

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Autors principals: Inagaki, Nobuya, Kondo, Kazuoki, Yoshinari, Toru, Ishii, Manabu, Sakai, Masaki, Kuki, Hideki, Furihata, Kenichi
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2014
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Original Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4168221/
https://ncbi.nlm.nih.gov/pubmed/25200141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40261-014-0226-x
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