Distinct regions of c-Mpl cytoplasmic domain are coupled to the JAK-STAT signal transduction pathway and Shc phosphorylation.

c-Mpl, a member of the hematopoietic cytokine receptor family, is the receptor for thrombopoietin. To investigate signal transduction by c-Mpl, a chimeric receptor, composed of the extracellular domain of human growth hormone receptor and the intracellular domain of c-Mpl, was introduced into the in...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Gurney, A L, Wong, S C, Henzel, W J, de Sauvage, F J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41680/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7777500/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.12.5292
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