Essential roles for GSK-3s and GSK-3 primed substrates in neurotrophin-induced and hippocampal axon growth

Glycogen synthase kinase-3β (GSK-3β) is thought to mediate morphological responses to a variety of extracellular signals. Surprisingly we found no gross morphological deficits in nervous system development in GSK-3β null mice. We therefore designed an shRNA that targeted both GSK-3 isoforms. Strong...

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Detalhes bibliográficos
Main Authors: Kim, Woo-Yang, Zhou, Feng-Quan, Zhou, Jiang, Yokota, Yukako, Wang, Yan-Min, Yoshimura, Takeshi, Kaibuchi, Kozo, Woodgett, James R., Anton, Eva, Snider, William D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167845/
https://ncbi.nlm.nih.gov/pubmed/17178402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2006.10.031
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