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Obesity- and aging-induced excess of central transforming growth factor-β potentiates diabetic development via an RNA stress response

The brain, in particular the hypothalamus, plays a role in regulating glucose homeostasis; however, it remains unclear if the brain is causally involved in diabetic development. Here, we identified that hypothalamic TGF-β is excessive under conditions of not only obesity but aging, which are two gen...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Yan, Jingqi, Zhang, Hai, Yin, Ye, Li, Juxue, Tang, Yizhe, Purkayastha, Sudarshana, Li, Lianxi, Cai, Dongsheng
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167789/
https://ncbi.nlm.nih.gov/pubmed/25086906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3616
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