An Intermediate Alemtuzumab Schedule Reduces the Incidence of Mixed Chimerism Following Reduced-Intensity Conditioning Hematopoietic Cell Transplantation for Hemophagocytic Lymphohistiocytosis

Reduced-intensity conditioning (RIC) improves the outcomes of hematopoietic cell transplantation (HCT) in patients with hemophagocytic lymphohistiocytosis (HLH). Proximal (ie, close to graft infusion) dosing of alemtuzumab is associated with a high incidence of mixed chimerism, whereas distal (ie, d...

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Autores principales: Marsh, Rebecca A., Kim, Mi-Ok, Liu, Chunyan, Bellman, Denise, Hart, Laura, Grimley, Michael, Kumar, Ashish, Jodele, Sonata, Myers, Kasiani C., Chandra, Sharat, Leemhuis, Tom, Mehta, Parinda A., Bleesing, Jack J., Davies, Stella M., Jordan, Michael B., Filipovich, Alexandra H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167781/
https://ncbi.nlm.nih.gov/pubmed/24035782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2013.09.001
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