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Epoxyeicosatrienoic acid analogue lowers blood pressure through vasodilation and sodium channel inhibition

Epoxyeicosatrienoic acids (EETs) contribute to haemodynamics, electrolyte homoeostasis and blood pressure regulation, leading to the concept that EETs can be therapeutically targeted for hypertension. In the present study, multiple structural EET analogues were synthesized based on the EET pharmacop...

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Autors principals: KHAN, Md. Abdul Hye, PAVLOV, Tengis S., CHRISTAIN, Sarah V., NECKÁŘ, Jan, STARUSCHENKO, Alexander, GAUTHIER, Kathryn M., CAPDEVILA, Jorge H., FALCK, John R., CAMPBELL, William B., IMIG, John D.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167712/
https://ncbi.nlm.nih.gov/pubmed/24707975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20130479
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