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Regulatory Variants and Disease: The E-Cadherin −160C/A SNP as an Example

Single nucleotide polymorphisms (SNPs) occurring in noncoding sequences have largely been ignored in genome-wide association studies (GWAS). Yet, amounting evidence suggests that many noncoding SNPs especially those that are in the vicinity of protein coding genes play important roles in shaping chr...

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Hlavní autoři: Li, Gongcheng, Pan, Tiejun, Guo, Dan, Li, Long-Cheng
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167656/
https://ncbi.nlm.nih.gov/pubmed/25276428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/967565
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