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Selection via pluripotency-related transcriptional screen minimizes the influence of somatic origin on iPSC differentiation propensity

The value of induced pluripotent stem cells (iPSCs) within regenerative medicine is contingent on predictable and consistent iPSC differentiation. However, residual influence of the somatic origin or reprogramming technique may variegate differentiation propensity and confound comparative genotype/p...

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Bibliographische Detailangaben
Hauptverfasser: Hartjes, Katherine A., Li, Xing, Martinez-Fernandez, Almudena, Roemmich, Alexa J., Larsen, Brandon T., Terzic, Andre, Nelson, Timothy J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167634/
https://ncbi.nlm.nih.gov/pubmed/24802033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1734
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