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Vertebrate kidney tubules elongate using a planar cell polarity-dependent, rosette-based mechanism of convergent extension
Cystic kidney diseases are a global public health burden, affecting over 12 million people(1). Although much is known about the genetics of kidney development and disease, the cellular mechanisms driving normal kidney tubule elongation remain unclear (2,3). Here, we used in vivo imaging to demonstra...
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| Glavni autori: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4167614/ https://ncbi.nlm.nih.gov/pubmed/23143599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2452 |
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